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World Health Organization recommended regimens without availability of sensitivity results, while regimens with availability of sensitivity results. In Indian set-up, most of the time either sensitivity test results are not available or if available they are usually highly unreliable. Keeping this fact in mind, depending upon past history of anti-tuberculosis treatment and resistance pattern, the author himself has used regimen containing Kanamycin, Ethionamide, PAS, Cyclosrine, and Fluroquinolone in treating multi-drug resistant tuberculosis and found to be effective in 31.71% of patients.

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Chandrasekaran S, Chauhan MM, Rajalaksmi R, Chaudhuri K, and Mahadev B. Initial drug resistance to anti-tuberculosis drugs in patients attending an urban district tuberculosis centre. Indian J Tuberc 1990; 37: 215-216.

Chandrasekaran S, Jagota P, and Chaudhuri K. Initial drug resistance to anti-tuberculosis drugs in urban and rural district tuberculosis programme. Indian J Tuberc 1992; 39: 171-175.


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