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Drug resistant tuberculosis has been reported since the early days of introduction of ant tubercular chemotherapy, but recently multi-drug resistant tuberculosis (MDR-TB), has been an area of growing concern, and is posing threat to global efforts of tuberculosis control.

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Multi-Drug Resistant Tuberculosis. ICMR 1999; 29 ( 10 and 11) : 105-114.

Cohn DL, Bustreo F, Raviglione MC. Drug resistant tuberculosis. Review of the world wide situation and the WHO / IUATLD Global Surveillance Project. International Union against Tuberculosis and Lung Diseases. Clin Infect Dis 1997; 24 (Supp l): S121-S130.

Pablos-Mendez A, Biokin N, Rieder HL, Bustreo F, Cohn DL, Lambregts van Weezenbeek CS, Kim SJ, Chaulet P and Nunn P. Global surveillance for antituberculosis drug resistance, 1994-1997. World Health Organization–International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance. N Engl J Med 1998; 338: 1641-1649.


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